臨床薬理の進歩 No.46

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--S group(n=37)45 (31-72)49 (28-57)231465.9 (47.0-96.0)63.7 (49.2-88.7)23.2 (18.1-32.6)24.0 (19.2-33.6)193.0 (132.0-242.0)240.3 (148.0-292.0)51.5 (28-93)64.5 (44.0-95.0)109.0 (50-163)118.5 (48.0-188.0)104.0 (41.0-219.0)91.00 (7.00-162.00)5.55 (4.8-6.4)5.45 (5.2-6.5)S group(N=37)5.36 (1.15-11.49)7.86 (2.41-17.86)3.72 (0.33-9.12)4.99 (1.53-14.49)18.39 (0.81-196.33)69.04 (0.12-327.83)0.65 (0.10-15.12)2.58 (0.10-58.69)H group(n=39)51.5 (42-58)47 (41-53)241573.0 (54.0-109.0)51.0 (40.0-68.0)25.5 (19.8-34.8)20.5 (17.8-29.8)215.0 (173.0-292.0)219.0 (151.0-273.0)48.0 (37.0-84.0)74.0 (38.0-109.0)127.5 (39.0-192.0)116.0 (57.0-175.0)113.0 (36-851)51.0 (27.0-153.0)5.5 (4.7-6.1)5.3 (4.1-5.8)H group (N=39)5.24 (1.45-11.66)8.41 (3.32-17.14)3.55 (0.53-9.01)5.66 (1.49-14.41)14.09 (4.64-44.78)11.63 (6.46-72.75)0.10 (0.10-7.19)0.10 (0.10-7.43)p valueN.S.N.S.<0.05<0.05<0.05<0.05N.S.N.S.N.S.N.S.N.S.N.S.N.S.N.S.N.S.N.S.p valueN.S.N.S.N.S.N.S.N.S.<0.05N.S.<0.05表1　研究対象者中央値（最小値−最大値）H group: 健康成人群、 S group: 統合失調症群BMI: body mass index、TC: total cholesterol、HDL-C: high-density lipoprotein cholesterol、LDL-C: low-density lipoprotein cholesterol、TG: triglycerides.表2　血液中および唾液中のアディポネクチン濃度中央値（最小値−最大値）H group: 健康成人群、 S group: 統合失調症群HMW: high molecular weight.Age (years)MaleFemaleGender (N)MaleFemaleBody weight (kg)MaleFemaleBMI (kg/m2)MaleFemaleTC (mg/dL)MaleFemaleHDL-C (mg/dL)MaleFemaleLDL-C (mg/dL)MaleFemaleTG (mg/dL)MaleFemaleHbA1c (%)MaleFemaleBlood Adiponectin (µg/mL)MaleFemaleBlood HMW Adiponectin (ng/mL)MaleFemaleSalivary Adiponectin (ng/mL)MaleFemaleSalivary HMW Adiponectin (ng/mL)MaleFemale140