00000低レベルマイクロサテライト不安定性の発がん機構の解明と免疫治療バイオマーカーの創出0.023173 (57%)133 (43%)0.10236 (76%)75 (24%)0.296 (2%)214 (69%)16 (5%)75 (24%)0.2287 (28%)219 (72%)0.9493 (30%)217 (70%)0.8522 (7%)49 (16%)86 (28%)116 (37%)38 (12%)0.11242 (78%)69 (22%)349 ± 1450.69153 (50%)0.91153 (50%)474 ± 4290.18153 (50%)0.37153 (50%)0.67270 (88%)37 (12%)0.14266 (85%)24 (8%)21 (7%)0.31248 (80%)63 (20%)(表1 前頁より続く)23 (82%)16 (67%)5 (18%)8 (33%)26 (93%)17 (71%)2 (7%)7 (29%)1 (4%)24 (86%)16 (67%)2 (7%)2 (7%)7 (29%)12 (44%)7 (29%)15 (56%)17 (71%)8 (31%)8 (33%)18 (69%)16 (67%)1 (4%)1 (4%)2 (7%)4 (17%)8 (29%)7 (29%)11 (39%)8 (33%)6 (21%)4 (17%)25 (89%)22 (92%)3 (11%)2 (8%)337 ± 122305 ± 8013 (46%)12 (52%)15 (54%)11 (48%)548 ± 392359 ± 25711 (41%)14 (61%)16 (59%)9 (39%)23 (82%)20 (87%)5 (18%)3 (13%)28 (100%)23 (96%)1 (4%)19 (68%)18 (75%)9 (32%)6 (25%)Absent212 (59%)Present146 (41%)Intestinal279 (77%)Diffuse84 (23%)Papillary7 (2%)Tubular254 (70%)Mucinous18 (5%)84 (23%)Absent106 (30%)Present251 (70%)Absent109 (30%)Present251 (70%)0-9%24 (7%)10-29%55 (15%)30-49%101 (28%)50-79%135 (37%)80-100%48 (13%)Transhiatal289 (80%)Transthoracic74 (20%)345 ± 140178 (50%)179 (50%)472 ± 418178 (50%)178 (50%)Absent313 (87%)Present45 (13%)R0317 (87%)R124 (7%)R222 (6%)285 (79%)78 (21%)Adjuvant chemotherapyHistological subtypesLauren classificationWHO classificationPoorly cohesiveLymphatic invasionVenous invasionKi-67 indexSurgical approachOperative time (min, mean ± SD)<319 (median)≧319 (median)Blood loss volume (g, mean ± SD)<351 (median)≧351 (median)Blood transfusionResection marginPreoperative complicationsNone or Clavien-Dindo <ⅢaClavien-Dindo ≧ⅢaSD, standard deviation. *p = 0.0037、**p = 0.0044、***p = 0.000851
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